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MemorySanitizer is a compile-time instrumentation layer in clang and GCC.
Together with AddressSanitizer mostly makes the run-time instrumentation
of Valgrind redundant. It is a little more tricky to set up, because
running with uninstrumented libraries will lead into false positives.

You will need an instrumented libc++, and you should use
-stdlib=libc++ instead of the default libstdc++. To build the
instrumented library, you can refer to
https://github.com/google/sanitizers/wiki/MemorySanitizerLibcxxHowTo
or you can adapt these steps that worked for me, for clang-8 version 8.0.1:

cd /mariadb
sudo apt source libc++-8-dev
cd llvm-toolchain-8-8.0.1
mkdir libc++msan; cd libc++msan
cmake ../libcxx -DCMAKE_BUILD_TYPE=Release -DLLVM_USE_SANITIZER=Memory \
-DCMAKE_C_COMPILER=clang-8 -DCMAKE_CXX_COMPILER=clang++-8

Then, in your MariaDB build directory, you have to compile with
libc++ and bundled libraries, such as WITH_SSL=bundled, WITH_ZLIB=bundled.
For uninstr...